Trusted in Florida since 2009 • Licensed providers • Evidence-based care
Stem Cell Therapy in Florida for Spine & Joint Pain
2009
2025
At Total Spine Wellness, we offer image-guided orthobiologic injections — including bone-marrow–derived cell procedures (BMAC) and platelet-rich plasma (PRP) — for carefully selected spine and large-joint conditions. Our practice emphasizes eligibility screening, clear expectations, and integration with rehabilitation so you know if and when biologics are appropriate and when surgery or another care pathway may be the better choice.

What is stem cell therapy for orthopedic pain?
For certain orthopedic conditions, cell-based and platelet-based injections are minimally invasive options that aim to reduce inflammation and support tissue repair in the spine and major joints. They are not universal cures; results depend on diagnosis, severity, and your commitment to a graded rehab program. We’ll compare these injections to other options during a consultation so you can make an informed decision.
Are you a candidate?
Likely candidates

Spine
degenerative disc disease, contained herniation with nerve symptoms, facet arthropathy, sacroiliac (SI) joint pain not improved with conservative care.

Joints
knee, hip, shoulder osteoarthritis; meniscal or labral degeneration; persistent tendinopathy (patellar, Achilles); tennis/golfer’s elbow.

Prior conservative management
Prior conservative management (e.g., physical therapy, activity modification) with incomplete relief.
Not ideal right now
Active infection, recent malignancy, poorly controlled diabetes, significant mechanical instability or deformity likely to require surgical correction, or inability to participate in rehab.
How stem cell treatment works
Stem cell treatment concentrates your body’s own regenerative cells (often from bone marrow) and places them into injured discs, joints, or tendons using image-guided injections. The cells and growth factors may reduce inflammation and support tissue repair while you rebuild strength through supervised rehab.
For patients who want more detail, see our explainer on how stem cell treatment works
Conditions we treat
Spine
- Disc degeneration or contained herniation — the goal is to reduce nerve inflammation and support disc biology while you rebuild capacity through graded loading.
- Facet and SI joint pain — targeted, image-guided injections reduce local inflammatory drivers and segmental pain.
Major joints & sport
- Knee / hip / shoulder osteoarthritis; meniscal or labral wear — treatment aims for pain and function gains and to delay progression when appropriate.
- Tendons / ligaments — persistent tendinopathy or partial-thickness tears may respond to platelet-based or marrow-based protocols paired with eccentric loading.
Compare options: What Is Stem Cell Therapy? And PRP Therapy Guide
Treatments we offer
Bone marrow concentrate (BMAC)
Autologous bone marrow aspirate is processed and injected under image guidance into the target joint, disc region, or enthesis when clinically indicated. We reserve marrow-based treatments for select spine and joint cases after eligibility screening and shared decision-making. Ask us about the evidence relevant to your diagnosis.
Platelet-rich plasma (PRP)
Concentrated platelets provide growth factors that can aid tendinopathy and mild-to-moderate osteoarthritis. Recent meta-analyses in knee OA report clinically meaningful functional improvement at 1–12 months and pain reduction at several time points; effect sizes and protocols vary. PRP therapy
Good to know: We individualize protocols. Some cases begin with PRP and progress to marrow-based injections if response is incomplete. Your clinician will discuss rationale, alternatives, and expected timelines in relation to imaging and exam findings.
Your visit — what to expect
Clinical evaluation & imaging review
- Confirm the pain generator(s), rule out red flags.
Shared plan
- Choose biologic type (if any), target structures, adjunct PT, and milestones.
Image-guided procedure
- Ultrasound and/or fluoroscopy in a sterile environment; local anesthesia and same-day discharge are typical.
Rehab & load management
- Staged return to work/sport coordinated with PT to protect the repair window.
Follow-up & outcomes tracking
- Pain/function measures at 6, 12, and 24+ weeks.
Safety, legality & FDA context (Florida)
We practice inside an FDA-aware framework emphasizing autologous, minimally manipulated tissues used for homologous purposes, with sterile technique, informed consent, and adverse-event monitoring. If your case suggests a better alternative (e.g., targeted ablation, endoscopic or reconstructive surgery), we will recommend that path.
Benefits — honest and evidence-aware
What biologics may help with:
Realistic timelines: early improvements are often seen in 4–8 weeks; meaningful gains typically develop over 3–6 months with a rehab program.
May reduce local inflammation.
May support tissue repair signaling.
May improve function and range of motion.
May delay or reduce the need for surgery in select cases.

BMAC vs PRP vs Surgery — quick compare
- PRP is often used for tendon problems and mild OA — it provides growth factors and can be effective for many soft-tissue issues.
- BMAC delivers a cellular concentrate from marrow and is used when deeper regenerative signaling is desirable (e.g., certain disc and joint cases).
- Surgery is indicated when structural instability, large tears, or mechanical failure are present.
We’ll help you choose the path that best matches your diagnosis and goals.

Why Total Spine Wellness
- Spine-led evaluations that map true pain generators before injections.
- 100% image-guided procedures (ultrasound/fluoro) for precise targeting.
- Rehab integration and staged load progression to support long-term improvement.
- Transparent discussions about candidacy, alternatives, and expectations — including surgical referral when indicated.
Explore our Florida services hub: Regenerative Medicine Treatments in Florida
Pricing & insurance
Initial evaluation and imaging review are often insurance-eligible. Biologic injections are typically cash-pay, with FSA/HSA options. We provide written estimates and financing discussions before scheduling. Treatment costs vary depending on diagnosis, number of targets, and biologic type.
Patient perspectives
FAQs
Is this legal and regulated in Florida?
Yes — when performed under FDA-aware standards using eligible HCT/P frameworks (autologous, minimally manipulated, homologous use) in an appropriate clinical setting. We review how this applies to your case during consent. (FDA guidance)
What evidence supports these injections?
Evidence is condition and protocol specific. For example, PRP for knee OA has randomized studies showing functional improvements and pain reduction. We’ll map the current evidence to your diagnosis and goals.
How soon might I notice changes?
Many patients observe early changes within 4–12 weeks, with continued gains over months when rehab is followed.
What are the risks?
Most common: temporary soreness/swelling. Serious complications are rare with sterile, image-guided procedures; however, all interventions carry some risk (infection, neurovascular injury).
How is PRP different from bone-marrow–derived injections?
PRP supplies growth factors from platelets; bone-marrow injections deliver a cellular concentrate with broader signaling potential. The right choice is diagnosis-driven.
How do these compare to surgery?
Some scenarios clearly require surgery (e.g., instability, major structural failure). Other situations may be appropriate for a biologics-first approach with monitored outcomes.
Next step
Send your MRI/X-rays for a free review. We’ll confirm candidacy, outline all appropriate options (including non-injection paths), and provide a clear written plan.